Top-selling next-generation probiotic

4.7 Based on 771 Reviews

Kijimea K53

(771)

Kijimea K53 combines a unique composition of 53 carefully selected probiotic strains - developed to naturally support and nurture your gut microbiome*.

  • Supports a healthy gut microbiome*

  • Promotes beneficial bacteria*

  • Promotes healthy bowel habits*

  • Supports intestinal regularity*

Kijimea
VERIFIED COMPANY
4.7Based on 771 reviews
Inspired by the natural diversity of the gut microbiome

Inspired by the natural diversity of the gut microbiome

Kijimea K53 is formulated to support the diversity of the gut microbiome with a unique and comprehensive blend of 53 diverse probiotic strains. Kijimea K53 helps good bacteria thrive in your gut and support a healthy gut microbiome*.

Your gut - center of your health

Your gut - center of your health

The intestinal microbiome hosts trillions of unique bacteria and plays a major role in human well-being through its intimate interaction with our central body functions — from the immune system to the central nervous system. Kijimea K53 combines 53 carefully selected probiotic strains to naturally support and nurture this delicate ecosystem*. Zinc acts as further support for your immune system function*.

Digestive Health

Digestive Health

Gut bacteria play a crucial role in processing the food we eat and extracting valuable nutrients from it. However, highly processed foods and the modern diet can negatively impact microbiome diversity - and therefore digestion and bowel habits. Kijimea K53 contains carefully selected strains, such as L. rhamnosus IMC 501 and L. paracasei IMC 502 – clinically validated to support healthy bowel habits and intestinal regularity*.

Kijimea K53 is validated in no less than 110 gold-standard trials

Randomized controlled trials are the gold standard in scientific research. Our key strains have been validated in no less than 110 gold-standard trials.

  • 15 x Increase in beneficial bacteria¹
  • +2.3 Improved intestinal regularity² 

    ¹In a 30-day clinical trial
    ²Compared to placebo. In a 12-week clinical trial.

Now save up to 40% with Kijimea K53

Returns: 30-day money-back guarantee.

One-Time purchase

3-month supply

3-month supply
$177$149

One time purchase.

1-month supply

1-month supply
$59

One time purchase.

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This is what happy Kijimea K53 product testers have to say

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Claudia

Verified buyer

Absolutely satisfied

"I am absolutely satisfied and will definitely continue to use it."

Angela

Verified buyer

They are very good for me

"I am very satisfied with these intestinal bacteria. They are very good for me! I think it's excellent that all the tablets are packed airtight!"

Customer photo
Customer photo
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Nadine

Verified buyer

The best..

"The best thing that ever happened to me."

Yves

Verified buyer

Absolutely recommended

"Well tolerated, great composition and absolutely recommended for sustainable health care!"

Customer photo
Customer photo
Customer photo

Marianna

Verified buyer

Good product!

Good product! I take it for myself every day, my health! Located right next to the glasses! The intestines are important!

Jutta

Verified buyer

Recommended by the family doctor!

Everything was great, recommended by the family doctor!

The reviews and user experiences presented on this website are based on voluntary feedback from real customers. They reflect individual experiences and may not be representative of typical results.

Shop with Confidence

30-Day Satisfaction Promise

If K53 doesn’t meet your expectations, request a full refund within 30 days of receiving your order—no questions asked.

Subscription Made Simple

Adjust your K53 delivery schedule or cancel your subscription anytime, hassle-free.

Complimentary US Shipping

Orders within the US ship within 1-2 business days. Flat-rate shipping available internationally.

Connect With Our Expert Team

Our K53 Science Support team is ready to assist with any questions about our research, health benefits, or product details.

Our Scientists

Our Scientific Board consists of scientists, professors, and doctors with a focus on the human microbiome.

I have been involved with Kijimea since its early days. From the outset, I was impressed by the uncompromising focus on microbiome research—translated into products that now help patients worldwide.

Martin Gschwender

MD - Digestive Health Specialist

From my practical experience I know that it is crucial for products to be supported by scientific evidence, especially if they are to be recommended in pharmacies. Kijimea has always put this evidence at the forefront of what it does.

Pia Glatte Bast

Pharmaceutical Technical Assistant & Intestinal Expert

What particularly impresses me is that Kijimea conducts its own studies in collaboration with some of the world's leading universities, applying the gold standard of scientific research—i.e.,
double-blind, placebo-controlled, and randomized. For me, this reliable data
and clear scientific evidence form the basis for genuine trust.

Joachim Bandlow

Expert in complementary medicine and naturopathy

Kijimea K53 Compared to Massively Promoted, One-Sized Gut Health Products

Kijimea product packshot
Others

# of Strains

53

< 20

Clinically tested strains

rarely tested clinically

Vitamin B₆ for protein metabolism*

rare

Moisture-proof alu-alu single packaging of each capsule

rarely blister packs

Our ingredients

53

probiotic strains

From science. For life. Formulated to support a healthy gut microbiome in its richness and diversity*.

Complete ingredient transparency

Clinically validated to promote beneficial bacteria and to support a healthy gut microbiome.*

Key strain:

  • B. animalis ssp. lactis MW21³

Promotes healthy bowel habits and supports intestinal regularity.*

Key strains:

  • L. rhamnosus IMC 501 (0.5 x 10⁹ CFU)
  • L. paracasei IMC 502 (0.5 x 10⁹ CFU)

Two of the world's most clinically studied strains, with 140+ publications.

Key strains:

  • L. rhamnosus GG (1 x 10¹⁰ CFU)
  • B. animalis ssp. lactis MW21³ (1 x 10¹⁰ CFU)
Supplement Facts
Our ingredients
Our ingredients

From science. For life.

  • Engineered for stability: Vcaps® Plus technology Vcaps® Plus technology protects moisture‑sensitive probiotics during the journey to your gut.
  • Custom-formed aluminum pocket Each capsule sits in a deep‑drawn blister pocket, engineered to hold it snugly in place.
  • Secure heat sealing The bottom film is heat‑sealed to the formed top film, creating a tight, hermetic seal around each capsule.
  • Double-wall aluminum chamber The double‑wall aluminum blister helps shield the strains from light, moisture, and oxygen.

Studies & clinical trials

Promotes beneficial bacteria*

>15x
Microbial diversity 1

Before

RA B.animalis BB12

After

RA B.animalis BB12

Improves intestinal regularity*

+2.3x
Improved intestinal Regularity 2

L.rhamnosus IMC501

L. paracasei IMC 502

Placebo

Absolute change in intestinal regularity
3.5
3.0
2.5
2.0
1.5
1.0
0.5
0.0
2x

L.rhamnosus IMC501

L. paracasei IMC 502

Placebo

2

Compared to placebo. In a 12-week clinical trial conducted on more than 800 adults.

Promotes beneficial bacteria*

>15x
Microbial diversity 1

Before

RA B.animalis BB12

After

RA B.animalis BB12

Questions? We are happy to help

What can I expect while taking Kijimea K53?

The intestinal microbiome hosts trillions of unique bacteria and plays a major role in human well-being through its intimate interaction with the body.
Kijimea K53 is a probiotic supplement which combines 53 carefully selected probiotic strains to support a healthy gut microbiome.*

How do I take Kijimea K53?

Take one capsule daily with a sufficient amount of water. Daily use for at least 12 weeks is recommended.

Do not exceed recommended daily dose. Keep out of reach of children.

Why should I take Kijimea K53 daily?

Consistent use can help to support the benefits of the clinically studied strains*.
We recommend a daily use for at least 12 weeks. When starting, your gut microbiome may take some time to adjust to the daily introduction of probiotics.

Do I need to refrigerate Kijimea K53?

No refrigeration is necessary.

Is Kijimea K53 safe to take while I'm pregnant or breastfeeding?

As with any dietary supplement or new health protocol, we recommend consulting a healthcare professional before you start consuming Kijimea K53 if you are pregnant or breastfeeding or trying to become pregnant, especially if taken in combination with other supplements containing zinc or vitamin B₆.

What pack sizes of Kijimea K53 are available?

Kijimea K53 is available in the following pack size: 30 capsules of 0.28 g each = 8.4 g

Is Kijimea K53 suitable for children?

Kijimea K53 is suitable for adults and children over the age of 14.
As with any dietary supplement or new health protocol for children under 18 years, we recommend consulting a healthcare professional before you start consuming Kijimea K53.

Is Kijimea K53 well tolerated?

There are no known side effects or interactions associated with the consumption of Kijimea K53. Consult your healthcare professional if you are taking, have recently taken or are planning to take any medicines together with Kijimea K53.

Kijimea K53 contains Milk.

Who is the distributor of Kijimea K53?

The product is distributed by Kijimea Inc. (120 Wall Street, New York, NY 10005)

How can I contact you?

Connect with our expert team: Our customer support team is ready to assist with any questions about our research, benefits or product details. Call us: +1-833-368-8468 Mon-Fri, 7-10 AM EST

References

Agamennone, V., Krul, C. A. M., Rijkers, G., & Kort, R. (2018). A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands. BMC gastroenterology, 18(1), 103. https://doi.org/10.1186/s12876-018-0831-x. PMID: 30078376; PMCID: PMC6091175.
Dronkers TMG, Ouwehand AC, Rijkers GT. Global analysis of clinical trials with probiotics. Heliyon. 2020 Jul 7;6(7):e04467. doi: 10.1016/.heliyon.2020.e04467. PMID: 32715136; PMCID: PMC7371762.
Jungersen M, Wind A, Johansen E, Christensen JE, Stuer-Lauridsen B, Eskesen D. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12(®). Microorganisms. 2014 Mar 28;2(2):92-110. doi:10.3390/microorganisms2020092. PMID: 27682233; PMCID: PMC5029483.
Li, Y. T., Xu, H., Ye, J. Z., Wu, W. R., Shi, D., Fang, D. Q., Liu, Y., & Li, L. J. (2019). Efficacy of Lactobacillus rhamnosus GG in treatment of acute pediatric diarrhea: A systematic review with meta-analysis. World journal of gastroenterology, 25(33), 4999–5016. https://doi.org/10.3748/wjg.v25.i33.4999. PMID: 31543689; PMCID: PMC6737314.
McFarland L. V. (2006). Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile disease. The American journal of gastroenterology, 101(4), 812-822. https://doi.org/10.1111/j.1572-0241.2006.00465.x PMID: 16635227.
Szajewska, H., Canani, R. B., Guarino, A., Hojsak, I., Indrio, F., Kolacek, S., Orel, R., Shamir, R., Vandenplas, Y., van Goudoever, J. B., Weizman, Z., & ESPGHAN Working Group for Probiotics Prebiotics (2016). Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Children. Journal of pediatric gastroenterology and nutrition, 62(3), 495–506. https://doi.org/10.1097/MPG.0000000000001081. PMID: 25756877.
Szajewska, H., & Kołodziej, M. (2015). Systematic review with meta-analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults. Alimentary pharmacology & therapeutics, 42(10), 1149–1157. https://doi.org/10.1111/apt.13404. PMID: 26365389.
Vandenplas, Y., Huys, G., & Daube, G. (2015). Probiotics: an update. Jornal de pediatria, 91(1), 6–21. https://doi.org/10.1016/j.jped.2014.08.005. PMID: 25458874.
³In the clinical studies referred as B. animalis ssp. Lactis BB-12®

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.